So here it was, 8:45am. I was loaded with coffee walking into a lecture on sleep. Dr. Lyles was blessed with a humerous outlook that helped all of us stay focused on not falling asleep! Here are some of the most profound facts:
If you sleep under 4 hours a night here is what happens to your body:
- Decrease in: mood, cognition, vigilence/reflexes, pain tolerence, immune function, glucose metabolism, pulmonary functions, growth/thyroid/prolactin/leptin hormones, seizure threshold
- Increase in: blood pressure, inflammatory ctokines, eveing cortisol, caloric intake after one night of deprivation.
- Every night you sleep under 4 hours a night.....IT TAKES 3 DAYS TO RECOVER!!!!!!
Psychiatric Disorders & Sleep
- Anxiety: Initial( can't fall asleep)/middle (wake up in the middle of the night) insomnia (50% GAD patients). Bedtime Worry/Tension
- Mania: Decreased need for sleep and decreasded total sleep time. Insomnia is predictive of relapse into mania.
- PTSD: Nightmares, Increase REM density, inability to maintain sleep.
- Panic Disorder: nocturnal panic attacks.
Depression & Sleep
- 20% of insomniacs have depression
- Sleep disturbance and fatigue are predictive of future depression
- Increased rates of relapse in remitted depressed patients with continuing sleep disturbance
- Initual (can't fall sleep), middle (wake up in the middle of the night) or terminal insomina
- Atypical depression goes into hypersmonia
- Single night sleep deprivation may temporarily decrease depression (a nap reverses it).
Fibromyalgia
- Diffuse musculoskeletal pain, chronic fatigue, non-restorative sleep and tender points in the muscles
- Unique presensce of Alpha waves during NREM sleep, esp. stages 3 & 4
- Highly associated with depression
- Treatment of sleep disorder is a core priority
Sleep Hygiene to Enhance Nighttime Sleep
- Avoid naps during the day
- Regular bedtime and rise times
- Avoid non-sleeping time in bed
- Avoid alcohol, nicotine, or caffiene
- Minimize exercise near bedtime
- Maximize bed comfort and room temperature
- Elimiate light and noise
- Get out of bed if unable to initiate sleep and try again later
- Avoid mental work near bedtime
Sleep: If You Don't Snooze: You Lose- Michael Lyles, M.D. Notes, Powerpoint. As seen from AACC World Conference, 2009.
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